IF IVF, Then PGS & NIPS? How Genetic Testing Can Say You About your Embryo?

Dr. Rimmi Singla has experience carrying out PGS, technique that detect genetic ailments and chromosomal abnormalities in embryos before they’re moved into the uterus. PGS technique is used to know whether the cells in an embryo comprise the normal number of chromosomes, which is 46. Subsequently an embryo raises in the lab, it is usually biopsied on day 5 (blastocyst stage). Some embryo cells are then sent to an exterior lab which uses technology to amount the number of chromosomes within each cell. Embryos with a standard amount of chromosomes are “euploid” and those with an abnormal number are “aneuploid.” The purpose of PGS is to avoid transferring an abnormal embryo into the uterus.

She also has experience performing NIPS (Non-invasive prenatal screening) are commonly performed tests for screening for Trisomy 21 (Down syndrome), Trisomy 18 (Edwards syndrome), Trisomy 13 & Monosomy X (Turner syndrome). These examinations are offered to expecting women who want to find out if they may be at increased risk of having a baby with any of the above syndromes.

 

Who benefits maximum from PGS?

 

All couples are at risk for consuming abnormal embryos. This issue increases significantly as a woman gets older. An abnormal embryo almost always fails to implant, or if it does, ends in a biochemical pregnancy (only hormone evidence of pregnancy), miscarriage, fetal death later in pregnancy, stillbirth or a baby with abnormalities.

 

Couples experiencing IVF may select PGS because they have male factor infertility, recurrent IVF failures, older age or a very large number of embryos. PGS can be used by those experiencing multiple miscarriages who may have diverse types of translocations where a piece of one chromosome breaks off and attaches to another chromosome resulting in a gain or loss of a cell’s genetic material. Use of PGS has grown rapidly because of support by many infertility specialist and patients who want to transfer a normal embryo.

 

For IVF recommend implanting more than one unscreened embryo. While this rises the success rate of IVF, it also raises your risk of carrying multiples. Your chance of actual IVF is the same when PGS screening identify one healthy embryo.

 

Talk to your fertility specialist about PGS & NIPS

The risk of having a baby with a chromosomal imbalance increases with the mother’s age, so Dr. Rimmi Singla may recommend PGS for older women. If you have recurrent miscarriages, you may also benefit from PGS. About half of all miscarriages are caused by chromosomal abnormalities, which can be identified with PGS.

When you’ve tried unsuccessfully to get pregnant and decide to undergo infertility treatment, there are many factors to consider. The same is true for pre-implantation genetic testing – it’s complicated. In this instance, your fertility specialist can help you discuss your options. Once your baby becomes a teenager, it’s also complicated – but then, you’ll be on your own!

LASER TREATMENT FOR Vaginal Rejuvenation & STRESS URINARY INCONTINENCE(SUI)

Laser Vaginal Rejuvenation is very common Female Genital Plastic Surgery technique. Several women pursue laser vaginal rejuvenation because they want to improve or enhance sexual satisfaction. Patients who suffer from pressure urinary incontinence (spontaneous loss of urine with laughing, coughing, sneezing, exercising etc.) can also have this complaint treated at the same time.

Further signs to be treated include: vaginal dryness, burning, irritation, dryness and sensation of pain and /or itching during sexual intercourse. It offers effective care for a highly diverse range of needs including:

  • Vaginal Tightening
  • Stress Urinary incontinence (SUI)
  • Vaginal Dryness & Recurrent infections
  • Post Menopause -GSM(Genito-Urinary Syndrome of Menopause)
  • Post Delivery Rehabilitation

laser vaginal rejuvenation or LVR is an innovative new technique, which is non-surgical in nature and can be used to treat vaginal atrophy and Stress Urinary Incontinence that is regularly produced due to age. However this is presently more popular as Vaginal tightening procedure.

Benefits of Vaginal Rejuvenation:This non-invasive treatment offers the following benefits:

  • Tightens the vaginal opening and vaginal canal
  • Tightens the vulva and reduces sagging labia
  • Improves vulvar skin tone and texture
  • Decreases vaginal dryness (atrophic vaginitis)
  • Reduces stress urinary incontinence
  • Increases sensitivity and may make it easier to achieve stronger, more frequent orgasms

Singla MediClinic offers the solution for vaginal tightening with the non-invasive, painless Laser Vaginal Rejuvenation Procedure ( Vaginoplasty ) done by Experienced laparoscopic Surgeon Dr. Rimmi Singla recognizes how significant vaginal health and sexual well-being are to a woman’s excellence of life. But we also understand that matters requiring vaginal rejuvenation can be sensitive for some women. For this motive, we strive to make you feel relaxed every step of the way.

You can also visit our website http://infertilitychandigarh.com and follow us on Google Plus, Instagram Facebook, Twitter and YouTube for the latest blog on fertility issues.

Categories  #ivf, IVF treatment

Male Infertility how you and your partner can get through it together

Infertility isn’t just a woman’s problem. Approximately 40% of couples, the male companion is either the main cause or a contributing cause of infertility.  A male fertility usually depends on the quantity and quality of his sperm. If the number of sperm a man ejaculates is low or if the sperm are of a poor quality, it can be difficult, and sometimes impossible, for him to cause a pregnancy.

There are many reasons of male infertility, and if your partner is facing one of them there are several ways you can help him deal with it. Dr. Rimmi Singla Director IVY Hospital, Mohali talks about what causes male infertility and how you and your partner can get through it together.

Known causes of male infertility

Sperm production problems • Chromosomal or genetic causes
• Undescended testes (failure of
the testes to descend at birth)
• Infections
• Torsion (twisting of the testis in scrotum)
• Varicocele (varicose veins of the testes)
• Medicines and chemicals
• Radiation damage
• Unknown cause
Blockage of sperm transport • Infections
• Prostate-related problems
• Absence of vas deferens
• Vasectomy
Sexual problems
(erection and ejaculation problems)
• Retrograde and premature ejaculation
• Failure of ejaculation
• Erectile dysfunction
• Infrequent intercourse
• Spinal cord injury
• Prostate surgery
• Damage to nerves
• Some medicines
Hormonal problems • Pituitary tumours
• Congenital lack of LH/FSH (pituitary problem from birth)
• Anabolic (androgenic) steroid abuse
Sperm antibodies • Vasectomy
• Injury or infection in the epididymis
• Unknown cause

If you and your partner are having trouble getting pregnant and would like to see a fertility specialist at Singla Mediclinic for an evaluation, Please call Dr. Rimmy Singla : +91-9815500448

Treatments Options for Male Infertility

After defining the cause of your husband’s infertility, our fertility specialist will put together a personalized treatment plan to put you on the path to parenthood. There are several non-invasive procedures available to help with male infertility:

  • Percutaneous Epididymal Sperm Aspiration (PESA): A method used collect seminal fluid from the epididymis by small needles.
  • Testicular Sperm Aspiration (TESA): A technique used to collect the sperm directly from the testes using small needles.
  • Trans-rectal Ultrasound of the Prostate with Seminal Vesicle Aspiration: A test using ultrasound to see if there is a blockage and, if so, pinpoint the location.
  • Microscopic Varicocel Repair: One of the most frequently used techniques to treat male infertility, this procedure emphases on reducing venous blood flow in the reproductive tract and improving testicular function by reducing scrotal temperature.

 

When dealing with male infertility, being diagnosed and defining an individualized treatment plan is a important first step. Make an appointment today to meet with our fertility expert at Singla Mediclinic & IVY Mohali to help you realize your dream of having a baby. You can reach us at 9815500448 & 9815550124.

 

Gallbladder Stone Surgery

Treatment for gallstones

Gallbladder Stone Surgery

Gallstones (biliary calculi) are stones made from cholesterol, bile pigment and calcium salts, typically in a combination that forms in the gallbladder. Gallstones are common complaint of the digestive system and affect around 15 per cent of people aged 50 years and over.

Other things that cause gallstones to form comprise the crystallisation of excess cholesterol in bile and the let-down of the gallbladder to blank entirely.

You might need quick treatment if stones block ducts and cause problems such as infections or inflammation of the gall bladder (cholecystitis) or pancreas (pancreatitis).

Laparoscopic Surgeon may remove your gallbladder (called a cholecystectomy)  if gallstones are triggering problems. Procedures include laparoscopic (‘keyhole’) cholecystectomy or open surgery. Gallbladder is not a vital organ, so your body can survive quite well without it.

Symptoms of gallstones

In many of cases, gallstones may not show any symptoms. The common symptoms of gallstones are following:

  • Discomfort or pain in the abdomen, specially right upper part, and back.
  • Rise in abdominal pain after eating a fatty meal
  • jaundice
  • Other symptoms like fever and pain, if the gallbladder becomes infected.

In what way Gallstones Diagnosed?

  • Blood tests
  • Complete blood count
  • Liver function test
  • Coagulation profile
  • Abdominal ultrasound
  • Cholescintigraphy (HIDA scan)
  • Endoscopic retrograde cholangiopancreatography (ERCP)
  • Magnetic resonance cholangiopancreatography (MRCP)

Causes and risk factors for gallstones

Gallstones are more common in women than in men. It’s quite common in overweight people and people with a family history of gallstones.

Treatment for gallstones
Treatment for gallstones

Treatment for gallstones

Treatment be subject to on the size and location of the gallstones, but may include:

  • Dietetic alterations – such as limiting or removing fatty foods and dairy products.
  • Medicines – some medications can liquify gallstones, but this treatment is only rarely given, due to side effects and a variable success rate

Surgical removal of the gallbladder or gallstones

Approximately 80 per cent of people with gallstone symptoms will need surgery. Surgeons may eliminate your entire gallbladder (cholecystectomy), and / or just the stones from bile ducts.

Procedures to remove the gallbladder include:

  • Laparoscopic cholecystectomy – ‘keyhole’ surgery. Surgeons makes several small incisions (cuts) through the skin, allowing access for a range of instruments. Surgeon eliminates the gallbladder through one of the incisions
  • Single Incision Laparoscopic surgery (SILS)——————
  • Open surgery (laparotomy) – Surgeon reaches the gallbladder through a wider abdominal incision. Patient need open surgery if patient has a complicated condition.
  • Medical factors to consider before cholecystectomy
  • Prior operation, Patient need to discuss some things with your doctor or surgeon, including:
  • Patient medical history, since some pre-existing conditions may affect decisions on surgery and anaesthetic
  • Some Medicines patient take on a regular basis, including over-the-counter arrangements
  • Any side effects from any medications.

Book an appointment with the Best gall bladder specialist Dr. Raman Singla in Chandigarh, Panchkula, Mohali, India at IVY Hospital & Singla Mediclinic.

Stem Cell Therapy new hope for Childless couples and recurrent IVF failures

Stem cells are indistinguishable cells that are existing in the embryonic, fetal, and adult phases of life and give growth to distinguished cells that make up the building blocks of tissue and organs. Due to their infinite source and high diversity potential, stem cells are considered as potential new therapeutic agents for the treatment of infertility. Stem cells could be stimulated in vitro to grow numerous numbers of specialized cells with male and female gametes signifying their potential use in reproductive medicine. During the previous few years, important progress in the derivation of male germ cells from pluripotent stem cells has been made. In addition, stem cell-based strategies for ovarian rebirth and oocyte creation have been planned as upcoming clinical treatments for treating childlessness in women.
Currently, there have been many patient cases wherein pregnancy could not be attained due to inadequate growth of the endometrium, perhaps because of recurrent D&C, genetic faults and premature ageing. Stem cells are perfectly powerful and are able to divide and renew themselves and turn into exact types of specialized cells such as blood or nerve cells. Stem cells are responsible for your baby’s organs, tissue and immune system development. The umbilical cord develops life during and after pregnancy. During the whole Pregnancy stage umbilical cord nurtures your baby’s life. It supplies oxygen-rich cells and nutrients from the mother’s placenta to her baby, also lets baby pump deoxygenated and depleted nutrient blood back to the placenta. This whole conversation procedure is protected by special tissue in order to ensure that the cord blood flow remains constant and steady. Stem cells therapeutic potential from the umbilical cord is well known.
In this treatment, the stem cells are extracted from the bone marrow. These stem cells develop endometrial angiogenic stem cells. Meanwhile, the uterine lining is cleaned. Then these are transplanted under strict aseptic conditions in the uterine cavity inside the Operation theatre. For relocation purpose in this procedure, sonographic techniques are used for endometrial lining in minimal duration. This is enough for the patient taking treatment to attain implantation during IVF Technique and is helpful for those who wish to give birth to their own child.

Stem cells could be inspired in vitro fertilization procedure in order to develop wide-ranging numbers of specialized cells. Singla Mediclinic & IVY Test Tube Baby Centre have the well-fortified advanced clinical structure with the Best Infertility specialist Doctor Rimmi Singla and the medical staff that will assist and coordinate with you in your whole fertility related treatment journey for successful outcomes in form of your own baby.
We provide the solutions to infertility problems using the stem cell therapies. Fertility issue in both male and female include Oligospermia, erectile dysfunction, recurrent IVF failure, endometriosis, Asherman syndrome etc. Stem cells are considered as new therapeutic agents for the treatment of infertility due to their widely available sources and high differentiation potential.

Singla Mediclinic -Dr. Rimmi Singla specializes in Recurrent Implantation Failure (RIF)

IVF, infertility treatment

Recurrent IVF Failure is the failure to achieve a pregnancy after several IVF efforts. Recurrent Implantation Failure (RIF) is very unsatisfying for patients and Doctors both.

Failure could be caused by many different issues such as:
•Attempted pregnancy at an advanced age.
•Structural complications with the uterus, ovaries or fallopian tubes.
•Endometrial receptivity problem.
•Systemic maternal factors.
•Genetic factors of (one of) the potential parents.

Other Reasons:

Uterine infection

Immune factors as a cause for IVF implantation failure

Thrombophilias

The mutual approach is taken by fertility/IVF specialists to treat recurrent implantation failure usually emphases on the following:
•Embryo quality.
•Efforts made to modify medication protocols.
•Utilizing chromosomal screening techniques like preimplantation genetic screening (PGS), or oocyte donation.

Image source: https://babygest.com/en/infertility-surrogacy/implantation-failure-and-recurrent-miscarriage/IVF failure

Just as important as providing sound medical advice and treatment, we also strive to foster strong partnerships with our patients through consistency and open communication, which help to ease the psychological burden of continuing fertility treatment under difficult circumstances, Singla Mediclinic specializes in Recurrent Implantation Failure (RIF) with the following approach:

•Friendly and receptive office environment with warm, caring staff.
•Experienced IVF Specialist practising exclusively in the Mohali,Chandigarh Panchkula, Punjab Location.
•Direct access to Doctor via email or phone with less than 24-hour response time.
•Extensive knowledge and experience in identifying and treating immunologic dysfunction and optimizing endometrial receptivity.
•Advanced embryology laboratory with PGS/PGD capabilities.

Recurrent failures//nil sperm//icsi//tesa//pesa//microtese// stem cell// for poor Endometrium// stem cell therapy//immunological therapy//DNA fragmentation index//picsi to choose for best sperm and various facilities under one roof// very friendly environment with renowned Dr Rimmy Singla // call at 91-9815500448//+91-9815550124

Helpline number for getting any information about Pregnancy and Covid-19 Contact: 9815500448, 9815507974

Labioplasty Cosmetic gynaecology

Labioplasty Cosmetic gynaecology, including LABIOPLASTY, is growing in popularity. Girls and women turn to these procedures various reasons. Some may be seeking relief from genital pain, while others may have cosmetic concerns about the look of their vagina. Still others may be hoping to enhance their sexual satisfaction.

Labiaplasty is a surgical procedure to trim and shape the vagina’s inner lips that may be elongated or asymmetrical that may cause pain or make them feel self-conscious. Long labia may cause pain during sexual intercourse, exercise or even while wearing jeans.


Labiaplasty is not the only type of cosmetic surgery that can be performed on the vagina. Vaginal rejuvenation, for example, involves tightening the vaginal and perineum areas, which can become stretched during childbirth. Book an appointment earliest and in warm atmosphere for get rid of this extra skin . Watsapp on 9815500448 .

Singla IVF & Laparoscopic Centre

Singla IVF & Laparoscopic Centre offers unique and quality healthcare facilities. Each and every patient is important to us and so we give best possible care to every couple visiting us for IVF & Laparoscopic services. It fulfill the dreams of couples who are unable to conceive naturally. We understand the apprehensions a couple faces while looking for infertility treatment.